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Is serum anti-cyclic citrullinated peptide level useful in the diagnosis of rheumatoid arthritis?

Authors
Kim, Duck-AnKim, Think-You
Issue Date
Apr-2012
Publisher
ELSEVIER SCIENCE BV
Keywords
Anti-CCP; ELISA; Rheumatoid arthritis; Diagnosis
Citation
CLINICA CHIMICA ACTA, v.413, no.7-8, pp.831 - 832
Indexed
SCIE
SCOPUS
Journal Title
CLINICA CHIMICA ACTA
Volume
413
Number
7-8
Start Page
831
End Page
832
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/165975
DOI
10.1016/j.cca.2012.01.022
ISSN
0009-8981
Abstract
Background To find out whether serum level of anti-cyclic citrullinated peptides (anti-CCP) could be useful in the diagnosis of rheumatoid arthritis (RA). Methods The study was performed against 1972 patients who visited Hanyang University Medical Center and were tested positive for anti-CCP. Results When test results were classified into 6 groups according to the anti-CCP level, diagnostic rates of RA in each group were distributed from 73.6% to 77.2%. The increase of serum level did not have any correlation with the diagnostic rate of RA. Conclusions The level of serum anti-CCP was not useful in the diagnosis of RA.
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