부검에서 신경염증 변화를 확인한 근위축측삭경화증 환자An Autopsy Case of Amyotrophic Lateral Sclerosis with Neuroinflammatory change
- Other Titles
- An Autopsy Case of Amyotrophic Lateral Sclerosis with Neuroinflammatory change
- Authors
- 하승현; 백원기; 김현영; 노민영; 황세진; 김승현
- Issue Date
- Feb-2012
- Publisher
- 대한신경과학회
- Keywords
- Amyotrophic lateral sclerosis; Autopsy; Neuroinflammation; Amyotrophic lateral sclerosis; Autopsy; Neuroinflammation
- Citation
- 대한신경과학회지, v.30, no.2, pp 128 - 131
- Pages
- 4
- Indexed
- KCI
- Journal Title
- 대한신경과학회지
- Volume
- 30
- Number
- 2
- Start Page
- 128
- End Page
- 131
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/166281
- ISSN
- 1225-7044
2288-985X
- Abstract
- Neuroinflammation such as reactive gliosis and microglial activations are important pathological findings of ALS. We present a first autopsy case of ALS in Korea related with neuroinflammatory change. A 67-year-old ALS patient suddenly expired due to accidental head trauma. Gross autopsy finding showed marked atrophic change in spinal cord.
Pathological finding include a marked loss of motor neurons, reactive gliosis and microglial infiltrations. These findings suggest neuroinflammation may play a role in pathogenesis of ALS.
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Collections - 서울 의과대학 > 서울 신경과학교실 > 1. Journal Articles

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