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Response patterns to bronchodilator and quantitative computed tomography in chronic obstructive pulmonary disease
- Authors
- Lee, Jae Seung; Huh, Jin Won; Chae, Eun Jin; Seo, Joon Beom; Ra, Seung Won; Lee, Ji-Hyun; Kim, Eun-Kyung; Lee, Young Kyung; Kim, Tae-Hyung; Kim, Woo Jin; Lee, Jin Hwa; Lee, Sang-Min; Lee, Sangyeub; Lim, Seong Yong; Shin, Tae Rim; Yoon, Ho Il; Sheen, Seung Soo; Oh, Yeon-Mok; Lee, Sang-Do
- Issue Date
- Jan-2012
- Publisher
- WILEY
- Keywords
- bronchodilators; chronic obstructive pulmonary disease; emphysema; salbutamol; volumetric computed tomography
- Citation
- CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, v.32, no.1, pp.12 - 18
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
- Volume
- 32
- Number
- 1
- Start Page
- 12
- End Page
- 18
- ISSN
- 1475-0961
- Abstract
- Background: Patients with chronic obstructive pulmonary disease (COPD) show different spirometric response patterns to bronchodilator, such that some patients show improvement principally in expiratory flow (forced expiratory volume in 1 s; FEV1), whereas others respond by improvement of lung volume (forced vital capacity; FVC). The mechanisms of these different response patterns to bronchodilator remain unclear. We investigated the associations between bronchodilator responsiveness and quantitative computed tomography (CT) indices in patients with COPD.
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Related Researcher
- Kim, Tae Hyung
- COLLEGE OF MEDICINE (DEPARTMENT OF INTERNAL MEDICINE)