Immunomodulatory Effect of Petasites japonicas on Murine SplenocytesImmunomodulatory Effect of Petasites japonicas on Murine Splenocytes
- Other Titles
- Immunomodulatory Effect of Petasites japonicas on Murine Splenocytes
- Authors
- Hwang,Yu-Jin; Woo,Hye-Im; Park,Dong-Sik; Kim,Jaehyun; Om,Ae-Son; Hwang,Kyung-A
- Issue Date
- Oct-2011
- Publisher
- 대한암예방학회
- Keywords
- Petasites japonicas; Mouse splenocyte; Immunomodulation; Cytokine
- Citation
- 대한암예방학회지, v.16, no.4, pp.311 - 317
- Indexed
- KCI
- Journal Title
- 대한암예방학회지
- Volume
- 16
- Number
- 4
- Start Page
- 311
- End Page
- 317
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/167392
- ISSN
- 2288-3649
- Abstract
- Recently, people are stepping up their efforts to prevent a disease and keep optimum health. Especially,the modulation of the immune responses to alleviate the diseases has been of interest for many years.
Although Petasites japonicas have been used as one of the traditional remedies as well as food sources,few studies on their immunomodulating effects have been reported. The result indicated that the extract was able to increase the proliferation B, T lymphocytes compared to no mitogen group. Additionally,we measured several cytokines such as IL-2, IL-4, IFNγ and TNFα which were related with immunoregulation.
The result of this study suggest that Petasites japonicas water extract could regulate the immune function by increasing the splenocyte proliferation. (Cancer Prev Res 16, 311-317, 2011)
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Collections - 서울 생활과학대학 > 서울 식품영양학과 > 1. Journal Articles
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