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에이즈 환자에서 발생한 비타민 B12 결핍에 의한 거대 적혈모구 빈혈open accessVitamin B12 deficiency megaloblastic anemia in a patient with acquired immunodeficiency syndrome

Other Titles
Vitamin B12 deficiency megaloblastic anemia in a patient with acquired immunodeficiency syndrome
Authors
김봉영김지은황순우이유화박정환문신제최지영송준석정종헌배현주
Issue Date
Jun-2011
Publisher
대한감염학회
Keywords
Human immunodeficiency virus (HIV); Megaloblastic anemia; Vitamin B12
Citation
Infection and Chemotherapy, v.43, no.3, pp.266 - 269
Indexed
SCOPUS
KCI
Journal Title
Infection and Chemotherapy
Volume
43
Number
3
Start Page
266
End Page
269
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168359
DOI
10.3947/ic.2011.43.3.266
ISSN
2093-2340
Abstract
Anemia is the most common hematologic finding in patients with advanced infections caused by human immunodeficiency virus (HIV) or advanced acquired immunodeficiency syndrome (AIDS). Among many etiologies of HIVassociated anemia, vitamin B12 deficiency plays an important role, mostly due to malabsorption or HIV enteropathy. We experienced a case of megaloblastic anemia caused by vitamin B12 deficiency in a male patient with an AIDS who had no structural gastrointestinal problem. He showed severe anemia, leukopenia, thrombocytopenia and suspicious neurologic manifestations such as aggravation of dementia and gait disturbance. With vitamin B12 and folate treatment, the patient's general condition and hematologic features were improved successfully.
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