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임상적으로 호전된 진행다초점백질뇌병증 환자의 백질 내 해부학적 연결성 추적관찰Serial Follow-up of White Matter Connectivity in a Patient with Progressive Multifocal Leukoencephalopathy Presenting Clinical Improvement
- Other Titles
- Serial Follow-up of White Matter Connectivity in a Patient with Progressive Multifocal Leukoencephalopathy Presenting Clinical Improvement
- Issue Date
- May-2011
- Publisher
- 대한신경과학회
- Keywords
- Key Words: Progressive multifocal leukoencephalopathy; Magnetic resonance spectroscopy; Tractography; Key Words: Progressive multifocal leukoencephalopathy; Magnetic resonance spectroscopy; Tractography
- Citation
- 대한신경과학회지, v.29, no.4, pp.347 - 351
- Indexed
- KCI
- Journal Title
- 대한신경과학회지
- Volume
- 29
- Number
- 4
- Start Page
- 347
- End Page
- 351
- ISSN
- 1225-7044
- Abstract
- Progressive multifocal leukoencephalopathy (PML) is a fatal disease that is characterized by progressive demyelination of the cerebral white matter due to JC viral infection. We report serial magnetic resonance spectroscopy (MRS) and tractography changes in a patient with PML. After a three-cycle treatment with cidofovir and cytarabine, the patient exhibited remarkable improvements in motor and cognitive functions. Follow-up MRS and tractography revealed regeneration of the white-matter fibers. This is the first consecutive neuroimaging study showing improvements in neurological symptoms using MRS and tractography.
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Collections - 서울 의과대학 > 서울 신경과학교실 > 1. Journal Articles
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Related Researcher
- Kim, Seung Hyun
- COLLEGE OF MEDICINE (DEPARTMENT OF NEUROLOGY)