Non-Dipper Pattern is a Determinant of the Inappropriateness of Left Ventricular Mass in Essential Hypertensive Patients
- Authors
- Kim, Bae Keun; Lim, Young-Hyo; Lee, Hyung Tak; Lee, Jae Ung; Kim, Kyung Soo; Kim, Soon Gil; Kim, Jeong Hyun; Lim, Heon Kil; Shin, Jinho
- Issue Date
- Apr-2011
- Publisher
- 대한심장학회
- Keywords
- Hypertension; Hypertrophy; left ventricular; Blood pressure monitoring; ambulatory
- Citation
- Korean Circulation Journal, v.41, no.4, pp 191 - 197
- Pages
- 7
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Circulation Journal
- Volume
- 41
- Number
- 4
- Start Page
- 191
- End Page
- 197
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168726
- DOI
- 10.4070/kcj.2011.41.4.191
- ISSN
- 1738-5520
1738-5555
- Abstract
- Background and Objectives: Inappropriately high left ventricular mass (iLVM) is known to be related to cardiovascular prognosis. A non-dipper pattern has a greater mean left ventricular (LV) mass than the dipper pattern in hypertensive patients. However, the appropriateness of LV mass in dipper or non-dipper patterns has not been adequately investigated. The aim of this study was to define the relationship between nocturnal dipping and the appropriateness of LV mass. Subjects and Methods: Using the ambulatory blood pressure monitoring (ABPM) database, the data of 361 patients who underwent ABPM and echocardiography was analyzed retrospectively. Appropriateness of LV mass was calculated as observed/predicted ratio of LV mass (OPR) using a Korean-specified equation. Nocturnal dipping was expressed as percent fall in systolic blood pressure (BP) during the night compared to the day. Results: Daytime, nighttime and 24 hours BP in hypertensive patients was 140.4 +/- 14.8 mmHg, 143.7 +/- 15.2 mmHg and 129.4 +/- 20.0 mmHg, respectively. OPR was 106.3 +/- 19.9% and nocturnal dipping was 10.2 +/- 10.9 mmHg. In a multiple linear regression model, 24 hours systolic BP (beta=0.097, p=0.043) and nocturnal dipping (beta=-0.098, p=0.046) were independent determinants of OPR as well as age (beta=0.130, p=0.025) and body mass index (BMI) (beta=0.363, p<0.001). Odds ratio of the non-dipper pattern was 2.134 for iLVM (p=0.021) and 3.694 for obesity (p<0.001; BMI >25 kg/m(2)). Conclusion: The non-dipper pattern is independently associated with iLVM in hypertensive patients as well as obesity.
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