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The Impact of Postoperative Radiotherapy on Dietary Function of Head and Neck Cancer Patients after Pharyngoesophageal Reconstruction with Free Jejunal Flapopen access

Authors
Chang, Lan SookWang, HyunAhn, Hee ChangLee, Tae HyeonTae, KyungPark, Seong Oh
Issue Date
May-2022
Publisher
MDPI
Keywords
dietary function; PORT; jejunal flap; dysphagia; pharyngoesophageal reconstruction
Citation
JOURNAL OF CLINICAL MEDICINE, v.11, no.10, pp.1 - 10
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF CLINICAL MEDICINE
Volume
11
Number
10
Start Page
1
End Page
10
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/170210
DOI
10.3390/jcm11102860
Abstract
This study investigated the impact of postoperative radiotherapy (PORT) on dietary function in patients who underwent pharyngoesophageal defect reconstruction using a free jejunal flap. A retrospective chart review of 36 patients who underwent circumferential pharyngoesophageal defect reconstruction using a free jejunal flap was performed. The European Organization for the Research and Treatment of Cancer head and neck cancer module questionnaire was used. Five items related to dietary function were selected and analyzed for changes in scores before and after PORT. Both the PORT and non-PORT groups showed improved dietary function before surgery, and no significant changes were noted at 3 and 12 months postoperatively. Repeated measures ANOVA showed that PORT had no significant impact on dietary function. In univariate analysis, no variable was a significant predictor of the score at 12 months, postoperatively. Previous radiotherapy and neck dissection had a close statistically significant relation. The multivariate analysis showed that neoadjuvant chemotherapy, previous radiotherapy, and neck dissection were significant predictors of the score at 12 months, postoperatively. PORT did not show a significant effect on the 12 months postoperative score. Free jejunal flap is an effective pharyngoesophageal defect reconstruction method that does not cause any dietary function disruption after PORT.
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서울 의과대학 > 서울 성형외과학교실 > 1. Journal Articles
서울 의과대학 > 서울 이비인후과학교실 > 1. Journal Articles

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Park, Seong Oh
COLLEGE OF MEDICINE (DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY)
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