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Voyage to minimal base editors
- Authors
- Song, Beomjong; Bae, Sangsu
- Issue Date
- Sep-2022
- Publisher
- NATURE PORTFOLIO
- Citation
- NATURE CHEMICAL BIOLOGY, v.18, no.9, pp.920 - 921
- Indexed
- SCIE
SCOPUS
- Journal Title
- NATURE CHEMICAL BIOLOGY
- Volume
- 18
- Number
- 9
- Start Page
- 920
- End Page
- 921
- ISSN
- 1552-4450
- Abstract
- Transposon-associated transposase B (TnpB) is the putative ancestor of Cas nucleases. A TnpB-based adenine base editor has now been developed that is small enough to be loaded into a single AAV vector without compromising editing activity.
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