"Brain Stunning" Atypical Feature of tPA Thrombolysis Following Aneurysm Embolization"Brain Stunning" 동맥류 색전술 후 tPA 혈전 용해의 비정형적 특징
- Other Titles
- "Brain Stunning" 동맥류 색전술 후 tPA 혈전 용해의 비정형적 특징
- Authors
- Park, Min Woo; Michael B. Horowitz; Yi,Hyeong Joong; Rishi Gupta
- Issue Date
- Oct-2006
- Publisher
- 대한신경외과학회
- Keywords
- Acute ischemic stroke; Endovascular coiling; Magnetic resonance imaging
- Citation
- 대한신경외과학회지, v.39, no.4, pp.300 - 302
- Indexed
- KCI
- Journal Title
- 대한신경외과학회지
- Volume
- 39
- Number
- 4
- Start Page
- 300
- End Page
- 302
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/172466
- ISSN
- 2005-3711
- Abstract
- "Stunning" represents prolonged contractile depression of any muscular component after alleviation of severe ischemia, as shown in reperfusion following acute myocardial ischemia or ischemic stroke. Clinically, it presents with no or delayed recovery past to thrombolytic therapy but its pathogenic mechanism is not fully uncovered yet. We describe a unique case of a 63-year-old woman, who was undertaken endovascular coiling for the aneurysms, deteriorated several hours later without known cause, and showed delayed clinical improvement over the next 3 days following thrombolysis. Immediate post-thrombolysis magnetic resonance imaging scan showed no apparent abnormality except for high signal intensity within the corresponding hemisphere. Reversible, but delayed nature of "brain stunning" can be explained by these images and it seems to be caused by a certain type of reperfusion injury. Key words:Acute ischemic stroke;Endovascular coiling;Magnetic resonance imaging;(Brain) Stunning;Thrombolytic therapy.
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