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9세 소아에서 아세트아미노펜에 의한 드레스증후군 1예open accessDrug reaction with eosinophilia and systemic symptom induced in a 9-year-old boy
- Other Titles
- Drug reaction with eosinophilia and systemic symptom induced in a 9-year-old boy
- Issue Date
- Jul-2016
- Publisher
- 대한 소아알레르기 호흡기학회
- Keywords
- Drug eruptions; Drug hypersensitivity; Eosinophilia; Acetaminophen
- Citation
- Allergy Asthma & Respiratory Diseases, v.4, no.4, pp.296 - 300
- Indexed
- KCI
- Journal Title
- Allergy Asthma & Respiratory Diseases
- Volume
- 4
- Number
- 4
- Start Page
- 296
- End Page
- 300
- ISSN
- 2288-0402
- Abstract
- The drug reaction with eosinophilia and systemic symptom (DRESS) is a severe adverse drug-induced reaction. Acetaminophen is extensively used as an over-the-counter drug as well as a medical therapeutic. In spite of its frequent use, drug eruptions related to DRESS caused by acetaminophen are rare. This case report describes a 9-year-old boy who experienced fever and maculopapular skin rashes after taking acetaminophen. Leukocytosis with marked eosinophilia and slightly elevated levels of liver enzymes were observed. Symptoms resolved after withdrawal of acetaminophen, followed by intravenous methylprednisolone administration. The diagnosis of DRESS induced by acetaminophen was confirmed by an oral challenge test after 2 months. No allergic reactions to ibuprofen were observed.
- Appears in
Collections - 서울 의과대학 > 서울 소아청소년과학교실 > 1. Journal Articles
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Related Researcher
- Yang, Seung
- COLLEGE OF MEDICINE (DEPARTMENT OF PEDIATRICS)