Retinal vascular occlusion during in vitro fertilization

Abstract

Purpose: To describe a case of human retinal vascular occlusion during in vitro fertilization. Methods: A single case report of a 30-year-old woman who developed decreased central vision in her left eye with inferonasal scotoma while on a gonadotropin-releasing hormone agonist treatment protocol. Results: The patient's laboratory tests and biochemical profile were normal. Fundoscopy revealed moderate tortuosity of both temporal vascular arcades and dilation of the inferior temporal vein with a blotchy hemorrhage. The superotemporal macular area was swollen and pale. Fluorescein angiography demonstrated an incomplete central retinal vein occlusion accompanied by branch retinal arterial occlusion in the left eye. Six months later, her vision improved to 20/32, and the retina recovered normal color. Conclusion: Retinal vascular occlusion can occur during a controlled ovarian hyperstimulation with gonadotropin-releasing hormone agonists.