Clostridium difficile 감염의 역학 및 치료Current epidemiology and treatment of Clostridium difficile infection
- Other Titles
- Current epidemiology and treatment of Clostridium difficile infection
- Authors
- 배현주
- Issue Date
- Dec-2010
- Publisher
- 대한감염학회
- Keywords
- Clostridium difficile; Epidemiology; Clinical characteristics; Diagnosis; Treatment
- Citation
- Infection and Chemotherapy, v.42, no.6, pp.362 - 368
- Indexed
- KCI
OTHER
- Journal Title
- Infection and Chemotherapy
- Volume
- 42
- Number
- 6
- Start Page
- 362
- End Page
- 368
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/173434
- DOI
- 10.3947/ic.2010.42.6.362
- ISSN
- 2093-2340
- Abstract
- With the emergence of B1/NAP1 strain of Clostridium difficile, epidemic feature of C.
difficile infection (CDI) has been changing in North America. Clinical manifestation of CDI caused by B1/NAP1 strain is more severe resulting in high mortality and complications, and relapse rate is higher. In Korea, the epidemic feature of CDI is not clearly demonstrated yet. Infection by B1/NAP1 strain was reported recently,but the prevalence of the infections by those strains seems to be not high yet. For the management of CDI, conventional treatment of vancomycin or metronidazole is still the choice of treatment, however, several clinical trials of CDI treatment are progressing; fidaxomicin, monoclonal antibody, toxoid vaccine, and luminal nontoxigenic C. difficile infusion. Thus, it is expected to have more effective treatment or prevention modality of CDI in near future.
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