Biogenic Nano-Synthesis; towards the Efficient Production of the Biocompatible Gold Nanoparticlesopen access
- Authors
- Ghodake, Gajanan; Eom, Chi-Yong; Kim, Si Wouk; Jin, EonSeon
- Issue Date
- Oct-2010
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Biogenic; AuNPs; Cell viability assay; Nontoxic green product
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.31, no.10, pp.2771 - 2775
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Volume
- 31
- Number
- 10
- Start Page
- 2771
- End Page
- 2775
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/173668
- DOI
- 10.5012/bkcs.2010.31.10.2771
- ISSN
- 0253-2964
- Abstract
- We present a rapid biogenic method for the production of nanoscale gold particles using pear extract. The formation and stability of pear-derived gold nanoparticles (Pear-AuNPs) were monitored by ultraviolet-visible spectroscopy. Their morphology, elemental composition and crystalline phase were determined by transmission electron microscopy, energy-dispersive X-ray spectroscopy and selected area electron diffraction. The average core size of crystalline Pear-AuNPs was in the range of 10 +/- 5 nm and the observed morphology was spherical. The X-ray photoelectron spectrum showed a strong peak for the pure 'Au' phase. The circular dichroism spectrum indicated the natural capping ability of the pear extract, which generated peptide-gold nanoparticles. These nanoparticles were stable in aqueous solution for two months. A cell viability assay of Pear-AuNPs showed biocompatibility with human embryonic kidney 293 cells. Accordingly, this eco-friendly process for the bio-mimetic production of Pear-AuNPs is nontoxic in nature; consequently, it will find potential application in nano-biotechnology.
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