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Rhodium-Catalyzed Domino Conjugate Addition-Cyclization Reactions for the Synthesis of a Variety of N- and O-Heterocycles: Arylboroxines as Effective Carbon Nucleophiles

Authors
Park, Ja OckYoun, So Won
Issue Date
May-2010
Publisher
AMER CHEMICAL SOC
Citation
ORGANIC LETTERS, v.12, no.10, pp.2258 - 2261
Indexed
SCIE
SCOPUS
Journal Title
ORGANIC LETTERS
Volume
12
Number
10
Start Page
2258
End Page
2261
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/175067
DOI
10.1021/ol100610v
ISSN
1523-7060
Abstract
Facile and efficient Rh(I)-catalyzed domino conjugate addition-cyclization reactions of olefins bearing two electrophilic sites and a pendant nucleophile with organoboroxines have been developed to afford a variety of N- and O-heterocycles, such as 3,4-dihydroquinolin-2(1H)-ones, 3,4-dihydrocoumarins, and pyrrolidin-2-ones, which constitute important motifs in biologically active natural and synthetic organic compounds.
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