Characteristics and Antioxidant Activity of Elsholtzia splendens Extract-Loaded Nanoparticles
- Authors
- Lee, Ji-Soo; Kim, Gun-Hee; Lee, Hyeon Gyu
- Issue Date
- Mar-2010
- Publisher
- AMER CHEMICAL SOC
- Keywords
- Elsholtzia splendens; chitosan nanoparticles; loading efficiency; antioxidant activity; beta-carotene bleaching assay
- Citation
- JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.58, no.6, pp.3316 - 3321
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Volume
- 58
- Number
- 6
- Start Page
- 3316
- End Page
- 3321
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/175389
- DOI
- 10.1021/jf904091d
- ISSN
- 0021-8561
- Abstract
- Elsholtzia splendens extract-loaded chitosan nanoparticles prepared by ionic gelation were characterized by particle size, zeta potential, entrapment efficiency, and loading efficiency. As the initial concentration of E splendens extract was increased, the loading efficiency and zeta potential significantly increased, whereas the entrapment efficiency and particle size significantly decreased. The optimum concentration of E splendens extract for maximum loading efficiency was found to be 0.8 mg/mL. Both free E splendens extract and E. splendens extract-loaded chitosan nanoparticles showed concentration-dependent antioxidant activity. However, the lipid peroxidation inhibitory activity of E. splendens extract was effectively enhanced when it was entrapped within chitosan nanoparticles. Chitosan nanoparticle encapsulation is therefore a potentially valuable technique for improving the antioxidant activity of E splendens extract.
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