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정상안과 황반질환 안의 퓨리에 도메인과 시간 도메인 빛간섭단층촬영에 의한 황반두께 비교Comparison of Macular Thickness Measurements Between Fourier-Domain and Time-Domain Optical Coherence Tomography in Normal Eyes and Eyes With Macular Diseases

Other Titles
Comparison of Macular Thickness Measurements Between Fourier-Domain and Time-Domain Optical Coherence Tomography in Normal Eyes and Eyes With Macular Diseases
Authors
고병우신용운이정민송유미이병로
Issue Date
Nov-2009
Publisher
대한안과학회
Keywords
Fourier domain OCT; Macular thickness; Macular volume; Stratus OCT
Citation
대한안과학회지, v.50, no.11, pp 1661 - 1668
Pages
8
Indexed
KCI
Journal Title
대한안과학회지
Volume
50
Number
11
Start Page
1661
End Page
1668
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/175824
DOI
10.3341/jkos.2009.50.11.1661
ISSN
0378-6471
2092-9374
Abstract
목적: 정상안에서 Fourier domain OCT (FD OCT)를 이용하여 황반두께 및 부피를 측정하여 Stratus OCT와 비교하였으며 황반질환안과 차이가 있는지 알아보고자한다. 대상과 방법: 23명 35안의 정상안과 24명 26안의 황반질환안 환자를 같은 시간대에 FD OCT와 Stratus OCT를 이용하여 황반두께와 총 황반부피를 구하여 서로 비교하였다. 결과: 전체 대상안의 중심와 망막두께는 FD OCT에서 251.49±79.45 μm, Stratus OCT에서 210.26±60.57 μm이었으며, 총황반부피는 각각 7.72±1.06 mm³, 7.04±0.96 mm³이었다. 9개의 ETDRS subfield 모든 영역에서 통계적으로 유의하게 FD OCT에서 Stratus OCT보다 더 두껍게 나타났다. 정상안 군과 황반질환안 군으로 나누어 비교했을 때에도 FD OCT가 통계적으로 유의하게 두껍게 나타났다. 결론: 정상안 군과 황반질환안 군 모두에서 망막두께 측정값이 FD OCT가 Stratus OCT보다 더 두꺼웠고 황반부피가 높았다. 이는 FD OCT는 망막색소상피 상부를 기준하여 시세포 외분절을 포함한 망막두께를 측정하기 때문이다. 따라서 FD OCT결과를 해석하거나 Stratus OCT 결과와 비교할 때는 이 점을 고려해야 한다.
Purpose: To define and measure macular thickness and volume using Fourier domain OCT (FD OCT) and compare the values with Stratus OCT in normal eyes and eyes with macular disease. Methods: On the same day, macular thicknesses of the ETDRS 9 subfield and total macular volumes were measured in 35 eyes of 23 normal subjects and 19 diseased eyes of 24 patients with FD OCT and Stratus OCT. The macular cube scan protocol for FD OCT and the fast macular thickness map protocol for Stratus OCT were used to measure macular thicknesses. Results: Foveal thickness of the central subfield in FD OCT (251.49±79.45 μm) was thicker than the value of Stratus OCT (210.26 ±60.57 μm) (p<0.001) in all eyes. Total macular volume was 7.72±1.06 mm³ and 7.04±0.96 mm³ for FD OCT and Stratus OCT, respectively (p<0.001). Retina thickness of the ETDRS 9 subfields in FD OCT was thicker than the value obtained using Stratus OCT. In addition, foveal thickness differences were statistically significant in both the normal and diseased eye groups. Conclusions: Macular thickness and total macular volume as measured by the FD OCT were larger than the values obtained using the Stratus OCT in both the normal and the diseased eye groups. The measuring algorithm of FD OCT defines the top of RPE as the outer retinal boundary, but Stratus OCT defines the outer retinal boundary as the IS/OS junction of the photoreceptor. Therefore, macular thicknesses of FD OCT are thicker than those of Stratus OCT. This difference should be considered when comparing the results of FD OCT with those of Stratus OCT.
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