Erythrocyte fatty acid profiles can predict acute non-fatal myocardial infarction
DC Field | Value | Language |
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dc.contributor.author | Park, Yongsoon | - |
dc.contributor.author | Lim, Jeehyun | - |
dc.contributor.author | Lee, Jaeung | - |
dc.contributor.author | Kim, Soon-gil | - |
dc.date.accessioned | 2022-12-20T20:21:30Z | - |
dc.date.available | 2022-12-20T20:21:30Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2009-11 | - |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/175968 | - |
dc.description.abstract | The risk of CHD has been linked to n-3 and bans-fatty acids. The purpose of the present study was to evaluate the hypothesis that lower n-3 fatty acids and higher traps-fatty acids in erythrocytes are associated with an increased risk of acute non-fatal myocardial infarction (MI), and that fatty acid profiles can discriminate MI cases from controls. Fifty cases with acute non-fatal MI and fifty age- and sex-matched controls without MI were recruited. The Omega-3 Index (the sum of EPA and DHA in erythrocytes) was significantly lower in cases than controls (9.57 (SEM 0.28) v. 11.81 (SEM 0.35) %; P<0.001), while total traps-fatty acids were significantly higher (1.01 (SEM 0.04) v. 0.56 (SEM 0.03) %; P<0.001). The Omega-3 Index was associated with decreased risk of MI (OR 0.08 (95 % CI 0.02, 0.38); P=0.001), while total traps-fatty acids were associated with an increased risk of MI (OR 7267 (95 % CI 6.68, 79074); P<0.001). The area under the receiver operating characteristic curve of fatty acid profiles was larger than that for traditional risk factors, suggesting that fatty acid profiles make a higher contribution to the discrimination of MI cases from controls compared with modified Framingham risk factors. In conclusion, a higher Omega-3 Index and lower traps-fatty acids in erythrocytes are associated with a decreased risk of MI. Furthermore, fatty acid profiles improve discrimination of acute non-fatal MI compared with established risk factors. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | CAMBRIDGE UNIV PRESS | - |
dc.title | Erythrocyte fatty acid profiles can predict acute non-fatal myocardial infarction | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Yongsoon | - |
dc.identifier.doi | 10.1017/S0007114509990298 | - |
dc.identifier.scopusid | 2-s2.0-73349129719 | - |
dc.identifier.wosid | 000272022500014 | - |
dc.identifier.bibliographicCitation | BRITISH JOURNAL OF NUTRITION, v.102, no.9, pp.1355 - 1361 | - |
dc.relation.isPartOf | BRITISH JOURNAL OF NUTRITION | - |
dc.citation.title | BRITISH JOURNAL OF NUTRITION | - |
dc.citation.volume | 102 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1355 | - |
dc.citation.endPage | 1361 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | BLOOD-CELL MEMBRANES | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | EICOSAPENTAENOIC ACID | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | ADIPOSE-TISSUE | - |
dc.subject.keywordPlus | DIETARY-INTAKE | - |
dc.subject.keywordPlus | SUDDEN-DEATH | - |
dc.subject.keywordPlus | N-3 | - |
dc.subject.keywordPlus | FISH | - |
dc.subject.keywordAuthor | Lipidome | - |
dc.subject.keywordAuthor | Myocardial infarction | - |
dc.subject.keywordAuthor | n-3 Fatty acids | - |
dc.subject.keywordAuthor | Trans-fatty acids | - |
dc.subject.keywordAuthor | Risk factors | - |
dc.identifier.url | https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/erythrocyte-fatty-acid-profiles-can-predict-acute-nonfatal-myocardial-infarction/940BADDEB44BACDC6CF09422AE465BB5 | - |
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