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Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infectionopen access
- Issue Date
- Oct-2009
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Neutropenia; Antineutrophil Antibody; Anti-Bacterial Agents
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.24, no.5, pp.975 - 978
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 24
- Number
- 5
- Start Page
- 975
- End Page
- 978
- ISSN
- 1011-8934
- Abstract
- Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe neutropenia during various antibiotic treatments. We detected 4 kinds (cefotaxim, augmentin, vancomycin, and tobramycin) of antibiotic-dependent antineutrophil antibodies by using the mixed passive hemagglutination assay (MPHA) technique with this child.
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Related Researcher
- Lee, Young Ho
- COLLEGE OF MEDICINE (DEPARTMENT OF PEDIATRICS)