gamma-Oryzanol-loaded calcium pectinate microparticles reinforced with chitosan: Optimization and release characteristics
DC Field | Value | Language |
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dc.contributor.author | lee, Ji-Soo | - |
dc.contributor.author | Kim, Jong Soo | - |
dc.contributor.author | Lee, Hyeon Gyu | - |
dc.date.accessioned | 2022-12-20T22:25:52Z | - |
dc.date.available | 2022-12-20T22:25:52Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2009-05 | - |
dc.identifier.issn | 0927-7765 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/176862 | - |
dc.description.abstract | Response surface methodology was used to optimize microparticle preparation conditions, including the ratio of pectin:gamma-oryzanol (OZ) (X-1), agitation speed (X-2), and the concentration of emulsifier (X-3), for maximal entrapment efficiency (EE) of OZ-loaded Ca pectinate microparticles. The optimized values of X1, X2, and X3 were found to be 2.72:5.28, 1143.5 rpm, and 2.61%, respectively. Experimental results obtained for the optimum formulation agreed favorably with the predicted results, indicating the usefulness of predicting models for EE. In order to evaluate the effect of chitosan-coating and blending on the release pattern of the entrapped OZ from microparticles, chitosan-coated and blended Ca pectinate microparticles were prepared. Release studies revealed that the chitosan treatments, especially the chitosan-coating, were effective ill Suppressing the release in both simulated gastric fluid (SGF) and intestinal fluid (SIF). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.title | gamma-Oryzanol-loaded calcium pectinate microparticles reinforced with chitosan: Optimization and release characteristics | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Hyeon Gyu | - |
dc.identifier.doi | 10.1016/j.colsurfb.2008.12.028 | - |
dc.identifier.scopusid | 2-s2.0-62349122377 | - |
dc.identifier.wosid | 000265317400008 | - |
dc.identifier.bibliographicCitation | COLLOIDS AND SURFACES B-BIOINTERFACES, v.70, no.2, pp.213 - 217 | - |
dc.relation.isPartOf | COLLOIDS AND SURFACES B-BIOINTERFACES | - |
dc.citation.title | COLLOIDS AND SURFACES B-BIOINTERFACES | - |
dc.citation.volume | 70 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 213 | - |
dc.citation.endPage | 217 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | IN-VITRO RELEASE | - |
dc.subject.keywordPlus | GEL BEADS | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | BRAN OIL | - |
dc.subject.keywordPlus | ALGINATE | - |
dc.subject.keywordPlus | MICROENCAPSULATION | - |
dc.subject.keywordPlus | TOCOPHEROL | - |
dc.subject.keywordPlus | PELLETS | - |
dc.subject.keywordAuthor | gamma-Oryzanol | - |
dc.subject.keywordAuthor | Ca pectinate microparticles | - |
dc.subject.keywordAuthor | Chitosan | - |
dc.subject.keywordAuthor | Entrapment efficiency | - |
dc.subject.keywordAuthor | Response surface methodology | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0927776508004864?via%3Dihub | - |
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