전신홍반루푸스에 동반된 IgA 신병증 1예A Case of IgA Nephropathy Associated with Systemic Lupus Erythematosus
- Other Titles
- A Case of IgA Nephropathy Associated with Systemic Lupus Erythematosus
- Authors
- 방소영; 김근호; 신동호; 박문향; 전재범
- Issue Date
- Mar-2009
- Publisher
- 대한류마티스학회
- Keywords
- IgA nephropathy; Systemic lupus erythematosus; Non-tuberculous mycobacterium
- Citation
- 대한류마티스학회지, v.16, no.1, pp.54 - 58
- Indexed
- KCI
- Journal Title
- 대한류마티스학회지
- Volume
- 16
- Number
- 1
- Start Page
- 54
- End Page
- 58
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/177050
- ISSN
- 2093-940X
- Abstract
- Renal involvement is frequently seen in patients with systemic lupus erythematosus (SLE). The occurrence of non-lupus nephritis, and especially IgA nephropathy, in SLE patients has rarely been reported. We describe here the case of a 30-year-old woman who had systemic lupus erythematosus and nontuberculous mycobacterial lung disease, and her biopsy of a renal lesion was unexpectedly diagnostic of IgA nephropathy. Although both IgA nephropathy and lupus nephritis are immune complex mediated diseases, their laboratory and histopathologic findings and the extra-renal clinical manifestations are different and these all support a different pathogenesis for the 2 diseases. Renal biopsy plays a crucial role in identifying and diagnosing renal lesions, which may have prognostic and therapeutic implications that are distinct from those of lupus nephritis. In conclusion, performing a renal biopsy in SLE patients who have urinary abnormalities is important since a correct diagnosis would permit the most appropriate treatment to be started and so avoid unnecessary immunosuppressive treatments.
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