강직성척추염에서 TNF 차단제와 포도막염TNF Inhibitors and Uveitis in Ankylosing Spondylitis
- Other Titles
- TNF Inhibitors and Uveitis in Ankylosing Spondylitis
- Authors
- 김희선; 김태종; 배상철; 유대현; 전재범; 김태환
- Issue Date
- Mar-2009
- Publisher
- 대한류마티스학회
- Keywords
- Ankylosing spondylitis; TNF inhibitor; Uveitis; Ankylosing spondylitis; TNF inhibitor; Uveitis
- Citation
- 대한류마티스학회지, v.16, no.1, pp.48 - 53
- Indexed
- KCI
- Journal Title
- 대한류마티스학회지
- Volume
- 16
- Number
- 1
- Start Page
- 48
- End Page
- 53
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/177074
- DOI
- 10.4078/jkra.2009.16.1.48
- ISSN
- 2093-940X
- Abstract
- Uveitis is the most common extra-articular manifestation of ankylosing spondylitis, and this occurs in 30∼50% of the patients with ankylosing spondylitis. The main symptoms of ankylosing spondylitis are usually highly responsive to TNF inhibitors, but the effects of TNF inhibitors on uveitis are inconsistent. We report here on sixteen cases of new onset uveitis during etanercept therapy in patients with ankylosing spondylitis and they had no histories of uveitis. The symptoms of ankylosing spondyltiis, other than the uveitis, were well controlled during etanercept therapy. Six patients had histories of infliximab therapy before undergoing etanercept therapy, and uveitis did not develop during this infliximab therapy. Uveitis can develop during the course of ankylosing spondylitis, yet there is a possibility of a temporal relationship between etanercept therapy and uveitis.
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