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Cortical thickness abnormality in juvenile myoclonic epilepsy
- Authors
- Tae, Woo Suk; Kim, Sun Hyung; Joo, Eun Yun; Han, Sun Jung; Kim, In Young; Kim, Sun I.; Lee, Jong-Min; Hong, Seung Bong
- Issue Date
- Apr-2008
- Publisher
- Dr. Dietrich Steinkopff Verlag
- Keywords
- juvenile myoclonic epilepsy; magnetic resonance imaging; gray matter; cortical thickness; epilepsy
- Citation
- Journal of Neurology, v.255, no.4, pp 561 - 566
- Pages
- 6
- Indexed
- SCIE
SCOPUS
- Journal Title
- Journal of Neurology
- Volume
- 255
- Number
- 4
- Start Page
- 561
- End Page
- 566
- ISSN
- 0340-5354
1432-1459
- Abstract
- Previous studies on gray matter concentration changes in patients with juvenile myoclonic epilepsy (JME) are inconsistent. To investigate cortical abnormality in JME differently, we measured the cortical thickness in 19 JME patients and 18 normal controls. Results showed that the cortical thicknesses of superior/middle/medial frontal gyri, and superior/middle/inferior temporal gyri were decreased in JME patients. Moreover, cortical thicknesses of precentral gyrus and medial orbital gyrus of right hemispheres were negatively correlated with disease duration. These findings suggest that JME brains have cortical gray matter atrophy in the frontal and temporal lobes.
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Related Researcher
- Lee, Jong Min
- COLLEGE OF ENGINEERING (서울 바이오메디컬공학전공)