Clinical characteristics and outcome for hepatitis C virus-positive diffuse large B-cell lymphoma
DC Field | Value | Language |
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dc.contributor.author | Park, Byeong-Bae | - |
dc.contributor.author | Kim, Jin Seok | - |
dc.contributor.author | Lee, Young-Yuel | - |
dc.contributor.author | Kang, Hye Jin | - |
dc.contributor.author | Ryoo, Baek Yeol | - |
dc.contributor.author | Kang, Jung Hun | - |
dc.contributor.author | Kim, Ho Young | - |
dc.contributor.author | Kim, Bong-Seog | - |
dc.contributor.author | Oh, Sung Yong | - |
dc.contributor.author | Kwon, Hyuk Chan | - |
dc.contributor.author | Won, Jong Ho | - |
dc.contributor.author | Kim, Kihyun | - |
dc.contributor.author | Park, Keunchil | - |
dc.contributor.author | Suh, Cheolwon | - |
dc.contributor.author | Kim, Won Seog | - |
dc.date.accessioned | 2022-12-21T04:49:29Z | - |
dc.date.available | 2022-12-21T04:49:29Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2008-01 | - |
dc.identifier.issn | 1042-8194 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/179083 | - |
dc.description.abstract | Several previous studies have addressed the association between hepatitis C virus (HCV) infection and non-Hodgkin lymphoma (NHL), but there are few studies on HCV-related diffuse large B-cell lymphoma (DLBL). We conducted this retrospective study to investigate the distinctive clinical characteristics and outcome for HCV-positive DLBL. We compared the clinical characteristics and outcomes of 32 HCV-positive DLBL cases from nine Korean institutions with those of 371 HCV-negative DLBL cases. A higher percentage of HCV-positive DLBL cases were associated with old age (60) than HCV-negative DLBL cases at diagnosis (59.4% vs. 36.1%, respectively, P=0.009) and HCV-positive cases were less likely than HCV-negative cases to have extranodal involvement (53.1% vs. 71.1%, respectively, P=0.044). The nodal presentation was the only independent factor favorably influencing the event free survival (EFS) in HCV-positive DLBL (HR=0.11, 95% CI; 0.01-0.95, P=0.012). In comparison to patients with HCV-negative DLBL, HCV-positive DLBL patients had a superior complete response rate (P=0.023) and EFS (P=0.02). In Korean patients, HCV-positive DLBL is more common with old age and has less extranodal involvement than does HCV-negative DLBL. The superior survival outcome for HCV-positive DLBL should be verified by further investigation, especially with respect to its correlation with transformed low-grade NHL. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.title | Clinical characteristics and outcome for hepatitis C virus-positive diffuse large B-cell lymphoma | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Byeong-Bae | - |
dc.identifier.doi | 10.1080/10428190701732861 | - |
dc.identifier.scopusid | 2-s2.0-38549109489 | - |
dc.identifier.wosid | 000252458200019 | - |
dc.identifier.bibliographicCitation | LEUKEMIA & LYMPHOMA, v.49, no.1, pp.88 - 94 | - |
dc.relation.isPartOf | LEUKEMIA & LYMPHOMA | - |
dc.citation.title | LEUKEMIA & LYMPHOMA | - |
dc.citation.volume | 49 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 88 | - |
dc.citation.endPage | 94 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Hematology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Hematology | - |
dc.subject.keywordPlus | NON-HODGKINS-LYMPHOMA | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordAuthor | hepatitis C virus | - |
dc.subject.keywordAuthor | diffuse large B-cell lymphoma | - |
dc.subject.keywordAuthor | clinical outcome | - |
dc.identifier.url | https://www.tandfonline.com/doi/full/10.1080/10428190701732861 | - |
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