장기적인 간헐적 산소 투여가 흰 쥐의 인지기능에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김찬 | - |
dc.contributor.author | 구승룡 | - |
dc.contributor.author | 김철현 | - |
dc.contributor.author | 김경헌 | - |
dc.contributor.author | 김동원 | - |
dc.contributor.author | 안해철 | - |
dc.date.accessioned | 2022-12-21T07:27:27Z | - |
dc.date.available | 2022-12-21T07:27:27Z | - |
dc.date.created | 2022-09-19 | - |
dc.date.issued | 2007-06 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/179932 | - |
dc.description.abstract | Background: Several studies have demonstrated that the transient administration of oxygen improves cognitive performance. However, the effect of long-term oxygen administration remains unknown. This study investigated the impact of long-term oxygen administration on cognitive enhancement. Methods: Six week old Sprague-Dawley rats (n = 46) were randomly allocated to one of three groups: the control (Control; n = 15), 30 min/day oxygen administration (Oxy30min; n = 16) and 60 min/day oxygen administration groups (Oxy60min; n = 15). The rats in all three groups were administered air or oxygen for 10 weeks. The Morris water maze test was employed to assess the latency (L & Lt), dwelling time (DT) and the total fraction above the mean dwelling time (FmDT) for cognitive performance. Results: Compared to the control group, the Oxy30min and Oxy60min groups showed no differences in their L and Lt. There was a dose-response trend due to oxygen administration. Compared to the control group, the Oxy60min group had a significantly improved DT (P < 0.05). The FmDT also significantly increased in both of the oxygen administration groups, which also showed a dose-response trend (P < 0.05). Conclusions: The present results suggest that long-term (10 weeks) oxygen administration can dose-dependently enhance cognitive performance. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한마취통증의학회 | - |
dc.title | 장기적인 간헐적 산소 투여가 흰 쥐의 인지기능에 미치는 영향 | - |
dc.title.alternative | Effects of Long-Term Intermittent Oxygen Administration on the Cognitive Function in Rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김동원 | - |
dc.identifier.doi | 10.4097/kjae.2007.52.6.687 | - |
dc.identifier.bibliographicCitation | Korean Journal of Anesthesiology, v.52, no.6, pp.687 - 693 | - |
dc.relation.isPartOf | Korean Journal of Anesthesiology | - |
dc.citation.title | Korean Journal of Anesthesiology | - |
dc.citation.volume | 52 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 687 | - |
dc.citation.endPage | 693 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART001211962 | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | cognitive function | - |
dc.subject.keywordAuthor | long-term oxygen administration | - |
dc.subject.keywordAuthor | water maze. | - |
dc.subject.keywordAuthor | cognitive function | - |
dc.subject.keywordAuthor | long-term oxygen administration | - |
dc.subject.keywordAuthor | water maze. | - |
dc.identifier.url | https://ekja.org/journal/view.php?number=6176 | - |
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