Blood Pulsation의 효과가 뇌 활성화에 미치는 영향을 알아보는 방법open accessEstimation Method for Brain Activities are Influenced by Blood Pulsation Effect
- Other Titles
- Estimation Method for Brain Activities are Influenced by Blood Pulsation Effect
- Authors
- 이원호; 구정훈; 이형래; 한기완; 박진식; 김재진; 윤강준; 김인영; 김선일
- Issue Date
- Jun-2007
- Publisher
- 대한의용생체공학회
- Keywords
- blood pulsation effect; BOLD; fMRI
- Citation
- 의공학회지, v.28, no.3, pp.338 - 343
- Indexed
- KCI
- Journal Title
- 의공학회지
- Volume
- 28
- Number
- 3
- Start Page
- 338
- End Page
- 343
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/179986
- ISSN
- 1229-0807
- Abstract
- BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. These observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.
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