Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: A possible association with oral midodrine treatment
- Authors
- Kim, Joong Seok; Lee, Kwang Soo; Lim, Sung Chul; Ahn, Jae Young; Song, In Uk; Kim, Yeong In; Kim, Bum Soo; Kim, Hee Tae
- Issue Date
- May-2007
- Publisher
- WILEY
- Keywords
- reversible posterior leukoencephalopathy syndrome; midodrine; orthostatic hypotension; multiple system atrophy
- Citation
- MOVEMENT DISORDERS, v.22, no.7, pp.1043 - 1046
- Indexed
- SCIE
SCOPUS
- Journal Title
- MOVEMENT DISORDERS
- Volume
- 22
- Number
- 7
- Start Page
- 1043
- End Page
- 1046
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180190
- DOI
- 10.1002/mds.21461
- ISSN
- 0885-3185
- Abstract
- We describe a 51-year-old man with a 3-year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause-and-effect relationship cannot be confirmed.
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