Should the lower limit of impaired fasting glucose be reduced from 110 mg/dL in Korea?
- Authors
- Ryu, Seungho; Shin, Hocheol; Chang, Yoosoo; Sung, Ki Chul; Song, Jaechul; Lee, Soo-Jin
- Issue Date
- Apr-2006
- Publisher
- W B SAUNDERS CO-ELSEVIER INC
- Citation
- METABOLISM-CLINICAL AND EXPERIMENTAL, v.55, no.4, pp.489 - 493
- Indexed
- SCIE
SCOPUS
- Journal Title
- METABOLISM-CLINICAL AND EXPERIMENTAL
- Volume
- 55
- Number
- 4
- Start Page
- 489
- End Page
- 493
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181582
- DOI
- 10.1016/j.metabol.2005.10.010
- ISSN
- 0026-0495
- Abstract
- The aims of this study were to determine if impaired fasting glucose should be redefined as a fasting plasma glucose (FPG) of 100 to 125 mg/dL (5.6-6.9 mmol/L) in Korea. A prospective cohort study was undertaken involving 13 189 male workers aged 30 to 59 years who did not have medication for diabetes, a history of any cancer, or a fasting glucose level of 126 mg/dL or higher at the initial examination between January 1999 to December 2000. Subjects were reexamined at periodic annual health examination over a 5-year period. The receiver operating characteristic curve for predicting the future onset of diabetes was derived by plotting the sensitivity against 1 - specificity for a baseline FPG of less than 126 mg/dL. The age- and body mass index-adjusted incidence density of type 2 diabetes mellitus was examined according to the percentile of the distribution for the baseline FPG. The baseline FPG for predicting the future onset of diabetes at a point on the receiver operating charactetistic curve that was closest to the ideal 100% sensitivity and 100% specificity was 92 mg/dL. There was a threshold for the age- and body mass index-adjusted incidence density of diabetes in the group with FPG of 93 to 95 mg/dL, at a mean of 93.9 mg/dL. Lowering the lower limit of impaired fasting glucose to 100 mg/dL (5.6 mmol/L) would optimize its sensitivity and specificity for predicting the future onset of diabetes in Korea.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 서울 의과대학 > 서울 직업환경의학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181582)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.