Macro-aspartate aminotransferase in a patient with chronic hepatitis C
- Authors
- Chung, Yong Woo; Sohn, Joo Hyun; Baek, Chang Hee; Kim, Jong Pyo; Jeon, Yong Cheol; Han, Dong Soo; Lee, Dong Hoo; Kee, Choon Suhk; Park, Il Kyu
- Issue Date
- Mar-2006
- Keywords
- Chronic hepatitis C; Macro-AST; Macroenzyme; Chronic hepatitis C; Macro-AST; Macroenzyme
- Citation
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, v.47, no.3, pp.229 - 232
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
- Volume
- 47
- Number
- 3
- Start Page
- 229
- End Page
- 232
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181681
- ISSN
- 1598-9992
- Abstract
- Macroenzymes are normal enzymes complexed with an immunoglobulin (usually IgG, rarely IgA or IgM). A number of macroenzymes have been reported in the literature. Among them, macro-AST has been detected in diseases such as acute and chronic hepatitis, various malignancies and autoimmune diseases, but usually not associated with any specific disease. We report a case of elevated AST activity in serum due to marco-AST formation in a female with chronic hepatitis C which was confirmed by AST isoenzyme electrophoresis. To our knowledge, this is the first report of macro-AST occurred in chronic hepatitis patient in Korea.
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