Epstein-Barr virus-associated Hodgkin's disease following renal transplantationopen access
- Authors
- Choi, Jung-Hye; Ahn, Myung-Ju; Oh, Young-Ha; Han, Sang-Woong; Kim, Ho-Jung; Lee, Young-Yeul; Kim, In-Soon
- Issue Date
- Mar-2006
- Publisher
- Korean Association of Internal Medicine
- Keywords
- Hodgkin' s disease; Post-transplant lymphoproliferative disorder; Renal transplantation
- Citation
- Korean Journal of Internal Medicine, v.21, no.1, pp.46 - 49
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- Korean Journal of Internal Medicine
- Volume
- 21
- Number
- 1
- Start Page
- 46
- End Page
- 49
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181683
- DOI
- 10.3904/kjim.2006.21.1.46
- ISSN
- 1226-3303
- Abstract
- Post-transplant lymphoproliferative disorders (PTLD) have been recognized as a complication of immunosuppression and occur with a reported incidence of 1 to 8% of recipients receiving solid organ transplantation. PTLD are classified into two major categories, polymorphic and monomorphic PTLD. The majority of the monomorphic PTLD cases are non-Hodgkin's lymphoma of B-cell origin. Hodgkin's disease is not part of the typical spectrum of PTLD; however, it has been rarely reported. We describe a case of Hodgkin's disease following renal transplantation. A 41-year-old man developed right cervical lymphadenopathy following renal transplantation 116 months previously for chronic renal failure of unknown origin. He had been taking cyclosporine, mycophenolate mofetil and prednisone. A lymph node biopsy revealed mixed cellularity Hodgkin's disease. Immunohistochemical staining was positive for CD30 and EBV-latent membrane protein-1. No other site of disease was identified. The immunosuppressive agents were reduced (mycophenolate mofetil was discontinued, cyclosporine dose reduced from 200 mg to 150 mg and prednisone continued at 5 mg). After 2 cycles of ABVD followed by radiation therapy (3600 cGy), he achieved complete remission.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 병리학교실 > 1. Journal Articles
- 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181683)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.