Expression of four growth factors in recessed extraocular muscles of rabbits
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Sun Young | - |
dc.contributor.author | Paik, Doo Jin | - |
dc.date.accessioned | 2022-12-21T11:54:56Z | - |
dc.date.available | 2022-12-21T11:54:56Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2006-03 | - |
dc.identifier.issn | 1542-8877 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/181714 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVE: The study was designed to determine the temporal expression of insulin-like growth factor (IGF)-I, IGF-II, basic fibroblast factor 2 (bFGF-2), and transforming growth factor beta 1 (TGF-beta 1) in recessed extraocular muscles. MATERIALS AND METHODS: Sixteen eyes of eight rabbits were subjected to conventional 4 mm recession of superior rectus muscles. Two rabbits were untreated as control. The rabbits were killed and their eyes were enucleated at 3 (group 3), 6 (group 6), 24 (group 24), and 72 (group 72) hours after the operation (two rabbits per group), and the expression of IGF-I, IGF-II, bFGF-2, and TGF-beta 1 was immunohistochemically examined. RESULTS: The peak levels of IGF-I, IGF-II, and TGF-beta 1 expression were observed in groups 24, 6, and 3, respectively. However, bFGF-2 was less expressed than the other growth factors in all groups. CONCLUSIONS: IGF-I, IGF-II, bFGF-2, and TGF-beta 1 in regenerating muscle cells were expressed by different kinetics, suggesting a distinct role of each growth factor during wound healing after recession of extraocular muscles. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SLACK INC | - |
dc.title | Expression of four growth factors in recessed extraocular muscles of rabbits | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Paik, Doo Jin | - |
dc.identifier.doi | 10.3928/1542-8877-20060301-08 | - |
dc.identifier.scopusid | 2-s2.0-33645499847 | - |
dc.identifier.wosid | 000236228600006 | - |
dc.identifier.bibliographicCitation | OPHTHALMIC SURGERY LASERS & IMAGING, v.37, no.2, pp.129 - 137 | - |
dc.relation.isPartOf | OPHTHALMIC SURGERY LASERS & IMAGING | - |
dc.citation.title | OPHTHALMIC SURGERY LASERS & IMAGING | - |
dc.citation.volume | 37 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 129 | - |
dc.citation.endPage | 137 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | IGF-I | - |
dc.subject.keywordPlus | POSTOPERATIVE ADHESIONS | - |
dc.subject.keywordPlus | HANG-BACK | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordPlus | SLEEVE | - |
dc.subject.keywordPlus | SITE | - |
dc.identifier.url | https://journals.healio.com/doi/10.3928/1542-8877-20060301-08 | - |
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