Multi-Modal Locomotion of Caenorhabditis elegans by Magnetic Reconfiguration of 3D Microtopographyopen access
- Authors
- Park, Jeong Eun; Yoon, Sunhee; Jeon, Jisoo; Kim, Chae Ryean; Jhang, Saebohm; Jeon, Tae-Joon; Lee, Seung Goo; Kim, Sun Min; Wie, Jeong Jae
- Issue Date
- Dec-2022
- Publisher
- WILEY
- Keywords
- 3D microtopography; Caenorhabditis elegans; magnetic shape-reconfiguration; microbarrier; multi-modal locomotion
- Citation
- ADVANCED SCIENCE, v.9, no.36, pp.1 - 13
- Indexed
- SCIE
SCOPUS
- Journal Title
- ADVANCED SCIENCE
- Volume
- 9
- Number
- 36
- Start Page
- 1
- End Page
- 13
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/185774
- DOI
- 10.1002/advs.202203396
- ISSN
- 2198-3844
- Abstract
- Miniaturized untethered soft robots are recently exploited to imitate multi-modal curvilinear locomotion of living creatures that perceive change of surrounding environments. Herein, the use of Caenorhabditis elegans (C. elegans) is proposed as a microscale model capable of curvilinear locomotion with mechanosensing, controlled by magnetically reconfigured 3D microtopography. Static entropic microbarriers prevent C. elegans from randomly swimming with the omega turns and provide linear translational locomotion with velocity of approximate to 0.14 BL s(-1). This velocity varies from approximate to 0.09 (for circumventing movement) to approximate to 0.46 (for climbing) BL s(-1), depending on magnetic bending and twisting actuation coupled with assembly of microbarriers. Furthermore, different types of neuronal mutants prevent C. elegans from implementing certain locomotion modes, indicating the potential for investigating the correlation between neurons and mechanosensing functions. This strategy promotes a platform for the contactless manipulation of miniaturized biobots and initiates interdisciplinary research for investigating sensory neurons and human diseases.
- Files in This Item
-
- Appears in
Collections - 서울 공과대학 > 서울 유기나노공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/185774)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.