마이코플라스마 폐렴에서 나타나는 폐외 증상의 발생률과 위험 인자open accessThe incidence and risk factors of extrapulmonary manifestations in Mycoplasma pneumoniae pneumonia
- Other Titles
- The incidence and risk factors of extrapulmonary manifestations in Mycoplasma pneumoniae pneumonia
- Authors
- 박유경; 박유나; 문지은; 김효빈; 신미용; 이 은; 김철홍; 이주석; 이용주; 김봉성; 김형영; 정성수; 김윤선; 김상영; 박초롱; 서주희; 심정연; 설인숙; 성명순; 송대진; 안영민; 오혜린; 유진호; 이경석; 장광천; 장윤영; 정혜리; 정은희; 최성민; 최윤정; 한만용; 김진택; 김창근; 양현종
- Issue Date
- Oct-2022
- Publisher
- 대한 소아알레르기 호흡기학회
- Keywords
- Mycoplasma pneumonia; Risk factors; Incidence; Extrapulmonary manifestation
- Citation
- Allergy Asthma & Respiratory Diseases, v.10, no.4, pp.207 - 214
- Indexed
- KCI
- Journal Title
- Allergy Asthma & Respiratory Diseases
- Volume
- 10
- Number
- 4
- Start Page
- 207
- End Page
- 214
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/189003
- DOI
- 10.4168/aard.2022.10.4.207
- ISSN
- 2288-0402
- Abstract
- associated with extrapulmonary manifestations (EPM). The incidence and risk factors for EPM in children are unknown.
Methods: This was a retrospective study involving 65,243 pediatric patients with CAP between 2010 and 2015 at 23 nationwide hospitals in South Korea. Medical records were reviewed to collect information regarding the clinical characteristics, radiological results, and laboratory findings. Logistic regression with multivariate analysis was performed to evaluate the risk factors associated with EPM in MP.
Results: The incidence of EPM was 23.9%, including elevation of liver enzymes (18.1%), mucocutaneous manifestations (4.4%), proteinuria (4.1%), cardiovascular and neurological manifestations (0.4%), hematologic manifestations (0.2%), and arthritis (0.2%). Statistical analysis showed that mucocutaneous manifestations significantly increased with elevated alanine aminotransferase (adjusted odds ratio [aOR], 3.623; 95% confidence interval [CI], 1.933-6.790) and atopic sensitization (aOR, 2.973; 95% CI, 1.615–5.475) and decreased with respiratory virus coinfection (aOR, 0.273; 95% CI, 0.084–0.887). Elevated liver enzymes were significantly associated with elevated lactate dehydrogenase (aOR, 3.055; 95% CI, 2.257–4.137), presence of pleural effusion (aOR, 2.635; 95% CI, 1.767–3.930), and proteinuria with respiratory virus coinfection (aOR, 2.245; 95% CI, 1.113–4.527).
Conclusion: Approximately 24% of pediatric patients with MP had various EPM. As the risk factors associated with each EPM were different, it is necessary to evaluate the various clinical aspects and findings of MP to predict and prepare for the occurrence of EPM.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 소아청소년과학교실 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.