Psychobiotics and fecal microbial transplantation for autism and attention-deficit/hyperactivity disorder: microbiome modulation and therapeutic mechanismsopen access
- Authors
- Kwak, Min-jin; Kim, Seung Hyun; Kim, Hoo Hugo; Tanpure, Rahul; Kim, Johanna Inhyang; Jeon, Byong-Hun; Park, Hyun-Kyung
- Issue Date
- Jul-2023
- Publisher
- FRONTIERS MEDIA SA
- Keywords
- autism spectrum disorder; attention-deficit; hyperactivity disorder; psychobiotics; fecal microbial transplantation; gut microbiome
- Citation
- FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v.13, pp 1 - 13
- Pages
- 13
- Indexed
- SCIE
SCOPUS
- Journal Title
- FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
- Volume
- 13
- Start Page
- 1
- End Page
- 13
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/189396
- DOI
- 10.3389/fcimb.2023.1238005
- ISSN
- 2235-2988
- Abstract
- Dysbiosis of the gut microbiome is thought to be the developmental origins of the host's health and disease through the microbiota-gut-brain (MGB) axis: such as immune-mediated, metabolic, neurodegenerative, and neurodevelopmental diseases. Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are common neurodevelopmental disorders, and growing evidence indicates the contribution of the gut microbiome changes and imbalances to these conditions, pointing to the importance of considering the MGB axis in their treatment. This review summarizes the general knowledge of gut microbial colonization and development in early life and its role in the pathogenesis of ASD/ADHD, highlighting a promising therapeutic approach for ASD/ADHD through modulation of the gut microbiome using psychobiotics (probiotics that positively affect neurological function and can be applied for the treatment of psychiatric diseases) and fecal microbial transplantation (FMT).
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Collections - 서울 의과대학 > 서울 소아청소년과학교실 > 1. Journal Articles
- 서울 공과대학 > 서울 자원환경공학과 > 1. Journal Articles
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