Clinical utility of directional eFLOW compared with contrastenhanced harmonic endoscopic ultrasound for assessing the vascularity of pancreatic and peripancreatic masses
- Authors
- Hwang, Jun Seong; Seo, Dong-Wan; So, Hoonsub; Ko, Sung Woo; Joo, Hyun Don; Oh, Dongwook; Song, Tae Jun; Park, Do Hyun; Lee, Sang Soo; Lee, Sung Koo; Kim, Myung-Hwan
- Issue Date
- Nov-2021
- Publisher
- ELSEVIER
- Keywords
- Pancreatic mass; Contrast-enhanced harmonic endoscopic ultrasound; Directional eFLOW
- Citation
- PANCREATOLOGY
- Indexed
- SCIE
SCOPUS
- Journal Title
- PANCREATOLOGY
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/190676
- DOI
- 10.1016/j.pan.2021.11.002
- ISSN
- 1424-3903
- Abstract
- Background: Contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) can be used for the differential diagnosis of pancreatic lesions by evaluating microvascular circulation and patterns of contrast enhancement. However, routine use of CEH-EUS is limited by its high cost, the lack of contrast agent availability and the absence of expertise with this technique. Directional eFLOW (D-eFLOW) (Aloka Co., Ltd., Tokyo, Japan) was introduced as a new high-definition modality that detects blood flow in micro-vessels. Because it uses built-in functions, it entails no additional cost and reduces time for examination. The present study compared the usefulness of D-eFLOW and CEH-EUS for differential diagnosis of pancreatic and peripancreatic lesions.
Methods: This retrospective study analyzed 130 patients who underwent EUS and D-eFLOW examinations from January 2016 to March 2020 to evaluate pancreatic and peripancreatic masses.
Results: All 130 patients underwent D-eFLOW and CEH-EUS examinations. Histological diagnoses were confirmed in 130 patients by EUS-FNA and/or surgery. D-eFLOW and CEH-EUS showed good correlation in evaluating the vascularity of pancreatic and peripancreatic tumors (Fisher's exact test, p < 0.05).
Conclusions: In evaluating the characteristics of tumorous lesions, vascularity detected by D-eFLOW showed good correlation with enhancement patterns of CEH-EUS. D-eFLOW can be considered a good alternative to CEH-EUS in diagnosing pancreatic and peripancreatic masses.
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