Cryolipolysis for abdominal subcutaneous fat reduction: A prospective, multicenter, single arm, clinical study
- Authors
- Choi, Sun Young; Park, Jae Wan; Koh, Young Gue; Jung, You Jin; Huh, Yun Jung; Ko, Eun Jung; Yoo, Kwang Ho; Seok, Joon; Kim, Soo Yeon; Jue, Mihn Sook; Ko, Joo Yeon; Kim, Beom Joon
- Issue Date
- Sep-2022
- Publisher
- WILEY
- Keywords
- 360 degrees surround cooling technology; body contouring; cryolipolysis; human participants; noninvasive technique
- Citation
- DERMATOLOGIC THERAPY, v.35, no.9, pp.1 - 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- DERMATOLOGIC THERAPY
- Volume
- 35
- Number
- 9
- Start Page
- 1
- End Page
- 8
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/191138
- DOI
- 10.1111/dth.15717
- ISSN
- 1396-0296
- Abstract
- Various treatment methods are used for noninvasive body contouring. To evaluate the efficacy and safety of a newly designed cryolipolysis device using a three-dimensional cooling method for abdominal fat reduction. Twenty-five participants with clinically apparent abdominal fat tissue participated in the study. The thickness of fat tissue below the umbilicus level was measured using a caliper at baseline and 12 weeks after the first treatment. The height of abdominal subcutaneous fat tissue on ultrasonography and participant satisfaction were assessed at every visit for 16 weeks. All adverse events (AEs) during the study period were recorded. p values <0.05 were considered statistically significant. Twenty-four participants completed this study; the mean BMI of participants was 29.34 +/- 2.36 kg/m(2). The mean thickness of abdominal subcutaneous fat was significantly lower at 12 weeks (40.4 +/- 6.8 mm, p < 0.001) than at baseline (49.3 +/- 8.5 mm). Differences in the height of abdominal subcutaneous fat compared to that at baseline were 1.02 +/- 0.41 cm (12 weeks, p < 0.001) and 1.13 +/- 0.44 cm (16 weeks, p < 0.001). Rates of abdominal subcutaneous fat reduction at 12 and 16 weeks compared to that at baseline were 28.45% and 31.13%, respectively. The ratio of abdominal circumference to hip circumference at 12 and 16 weeks was significantly decreased compared to that at baseline. Most participants (95.8%) reported improvement in satisfaction scores at 16 weeks. There were no serious AEs during the entire study period. The study demonstrated the efficacy of a noninvasive cryolipolysis device using a three-dimensional cooling method for reducing abdominal subcutaneous fat.
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