Blended extract of oat, sorghum, adzuki bean, finger millet, and proso millet improved hyperglycemia and insulin resistance in the streptozotocin–nicotinamide-induced diabetic rats
DC Field | Value | Language |
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dc.contributor.author | Yang, Yun Sun | - |
dc.contributor.author | Jeong, Eun Woo | - |
dc.contributor.author | Baek, Youjin | - |
dc.contributor.author | Go, Gwang-woong | - |
dc.contributor.author | Lee, Hyeon Gyu | - |
dc.date.accessioned | 2023-11-14T08:51:05Z | - |
dc.date.available | 2023-11-14T08:51:05Z | - |
dc.date.created | 2023-07-04 | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/192415 | - |
dc.description.abstract | Grains contain bioactive components that potentially have protective effects on chronic diseases such as diabetes. The anti-diabetic effects of blended grain ethanol extract (BGE) were evaluated in streptozotocin–nicotinamide (STZ–NA)-induced diabetic rats. BGE was prepared by mixing oat, sorghum, adzuki bean, finger millet, and proso millet (30:30:15:15:10). The rats were assigned into four groups, normal control, diabetic model control (DM), STZ–NA rats administered 200 mg/kg body weight (bw) of metformin, and STZ–NA rats administered 500 mg/kg bw of BGE (BGE). After 6 weeks of administration, the homeostatic model assessment of insulin resistance (12%) in BGE decreased compared to DM. Strikingly, the fasting blood glucose (23%) and oral glucose tolerance test (15%) were improved in BGE compared to DM. BGE also increased insulin immunoreactivities in pancreatic β-cells. In sum, BGE exhibits anti-hyperglycemic effects by improving fasting glucose levels and insulin secretion from pancreatic β-cells in the STZ–NA-induced diabetic rats. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | The Korean Society of Food Science and Technology | - |
dc.title | Blended extract of oat, sorghum, adzuki bean, finger millet, and proso millet improved hyperglycemia and insulin resistance in the streptozotocin–nicotinamide-induced diabetic rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Go, Gwang-woong | - |
dc.contributor.affiliatedAuthor | Lee, Hyeon Gyu | - |
dc.identifier.doi | 10.1007/s10068-023-01340-y | - |
dc.identifier.scopusid | 2-s2.0-85161960127 | - |
dc.identifier.wosid | 001008445900002 | - |
dc.identifier.bibliographicCitation | Food Science and Biotechnology, v.32, no.10, pp.1415 - 1421 | - |
dc.relation.isPartOf | Food Science and Biotechnology | - |
dc.citation.title | Food Science and Biotechnology | - |
dc.citation.volume | 32 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1415 | - |
dc.citation.endPage | 1421 | - |
dc.type.rims | ART | - |
dc.type.docType | Article in press | - |
dc.identifier.kciid | ART002981156 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | RICH EXTRACTS | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordAuthor | Adzuki bean | - |
dc.subject.keywordAuthor | Finger millet | - |
dc.subject.keywordAuthor | Oat | - |
dc.subject.keywordAuthor | Proso millet | - |
dc.subject.keywordAuthor | Sorghum | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s10068-023-01340-y | - |
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