Diagnostic Clues for Women with Acute Surgical Abdomen Associated with Ruptured Endometriomaopen access
- Authors
- Keum, Jihyun; Lee, Won Moo; Choi, Joong Sub; Bae, Jaeman; Cho, Seongsil; Kang, Bo Kyeong
- Issue Date
- Aug-2023
- Publisher
- Multidisciplinary Digital Publishing Institute (MDPI)
- Keywords
- CA 125; CA 19-9; CRP; endometrioma; ruptured state
- Citation
- Journal of Personalized Medicine, v.13, no.8, pp.1 - 12
- Indexed
- SCIE
SCOPUS
- Journal Title
- Journal of Personalized Medicine
- Volume
- 13
- Number
- 8
- Start Page
- 1
- End Page
- 12
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/192948
- DOI
- 10.3390/jpm13081226
- ISSN
- 2075-4426
- Abstract
- (1) Background: An investigation of the preoperative diagnostic clues used to identify ruptured endometrioma by comparing the ruptured and unruptured states in patients who underwent laparoscopic operations due to endometrioma. (2) Methods: Patients with ruptured endometriomas (14 patients) and unruptured endometriomas (60 patients) were included, and clinical symptoms, laboratory findings, and radiological findings were analyzed. (3) Results: There were no significant differences in age, parity, last menstrual cycle days, or median size of endometrioma between two groups (group A: ruptured; group B: unruptured). The median serum level of CA 125 was 345.1 U/mL in group A and 49.8 U/mL in group B (p = 0.000). The median serum levels of CA 19-9 in group A and B were 46.0 U/mL and 19.1 U/mL, respectively (p = 0.005). The median serum level of CRP in group A was 1.2 g/dL, whereas it was 0.3 in group B (p = 0.000). ROC analysis showed that the optimal CA 125 cutoff value was 100.9 U/mL; the optimal CA 19-9 cutoff value was 27.7 U/mL; and the optimal CRP cutoff value was 1.0 g/dL. (4) Conclusions: Ruptured endometrioma can be diagnosed preoperatively using a combination of clinical symptoms, laboratory findings, and radiological findings. If a physician suspects a ruptured endometrioma, surgery should be performed to ensure optimal prognosis.
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