Retinal Thickness Analysis Using Optical Coherence Tomography: Diagnostic and Monitoring Applications in Retinal Diseases

Abstract

Retinal thickness analysis using optical coherence tomography (OCT) has become an indispensable tool in retinal disease management, providing high-resolution quantitative data for diagnosis, monitoring, and treatment planning. This analysis has been found to be particularly useful for both diagnostic and monitoring purposes across a wide range of retinal diseases, enabling precise disease characterization and treatment evaluation. This paper explores its applications across major retinal conditions, including age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and inherited retinal diseases. Emerging roles in other diseases such as neurodegenerative diseases and retinal drug toxicity are also highlighted. Despite challenges such as variability in measurements, segmentation errors, and interpretation difficulties, advancements in artificial intelligence and machine learning have significantly improved accuracy and efficiency. The integration of retinal thickness analysis with telemedicine platforms and standardized protocols further underscores its potential in delivering personalized care and enabling the early detection of ocular and systemic diseases. Retinal thickness analysis continues to play a pivotal and growing role in both clinical practice and research, bridging the gap between ophthalmology and broader medical fields.