A Randomized Controlled Trial Comparing Colonoscopic Enema With Additional Oral Preparation as a Salvage for Inadequate Bowel Cleansing Before Colonoscopy
- Authors
- Yang, Hyo-Joon; Park, Dong Il; Park, Soo-Kyung; Kim, Sunyong; Lee, Taeheon; Jung, Yunho; Eun, Chang Soo; Han, Dong Soo
- Issue Date
- Sep-2019
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- colonoscopy; cathartics; salvage therapy; enema; polyethylene glycols
- Citation
- JOURNAL OF CLINICAL GASTROENTEROLOGY, v.53, no.8, pp.E308 - E315
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CLINICAL GASTROENTEROLOGY
- Volume
- 53
- Number
- 8
- Start Page
- E308
- End Page
- E315
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/2154
- DOI
- 10.1097/MCG.0000000000001087
- ISSN
- 0192-0790
- Abstract
- Goals:
The goal of this study was to evaluate the noninferiority of colonoscopic enema to additional oral preparation in salvage bowel cleansing for inadequate preparation for a morning colonoscopy.
Background:
Colonoscopic enema, administering additional cathartics into the right colon through the colonoscope accessory channel, is suggested to rescue poor bowel preparation for a colonoscopy but lacking comparative study.
Study:
In this prospective, randomized, actively-controlled, parallel group, noninferiority trial, consecutive outpatients and health checkup recipients aged from 19 to 70 years with inappropriate bowel preparation during an elective colonoscopy were enrolled to receive either a colonoscopic enema of 1 L polyethylene glycol (PEG) (enema group) or additional oral intake of 2 L PEG (oral group). The primary endpoint was the proportion of adequate bowel preparation evaluated using the Boston Bowel Preparation Scale.
Results:
Overall, 131 participants were randomized. Adequate bowel preparation was achieved in 53% (35/66) of the enema group, which was significantly inferior to the oral group (81.5%; 53/67) with a difference of −28.5% (95% confidence interval, −44.1, −12.9; P=0.001). The largest difference in the proportion of adequate bowel preparation was observed in the right colon (57.8% in the enema group vs. 86.9% in the oral group; P<0.001), followed by the transverse colon (85.9% vs. 98.4%; P=0.017) and the left colon (90.6% vs. 96.7%; P=0.274).
Conclusions:
The colonoscopic enema of 1 L PEG was inferior to the additional oral ingestion of 2 L PEG regarding efficacy as a salvage bowel preparation in adults with inadequate bowel cleansing for colonoscopy.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/2154)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.