Comparison of screening strategies for prevalent vertebral fractures in South Korea: vertebral fracture assessment vs. spine radiographyopen access
- Authors
- Oh, Sung-Hee; Kim, Dam; Lee, Young Eun; Kim, Deog-Yoon; Lee, Yu Kyung; Lee, Joo-Hyun; Bae, Sang-Cheol; Choi, Yun Young; Pyo, Junhee; Ahn, Jeonghoon; Sung, Yoon-Kyoung
- Issue Date
- Feb-2018
- Publisher
- BIOMED CENTRAL LTD
- Keywords
- Spinal fracture; Radiography; Diagnostic imaging; Cost effectiveness; Radiation
- Citation
- BMC MUSCULOSKELETAL DISORDERS, v.19
- Indexed
- SCIE
SCOPUS
- Journal Title
- BMC MUSCULOSKELETAL DISORDERS
- Volume
- 19
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/2425
- DOI
- 10.1186/s12891-018-1958-1
- ISSN
- 1471-2474
- Abstract
- Background: Vertebral Fracture Assessment (VFA) is a useful tool to detect the vertebral fracture (VF) with low cost and radiation exposure. We aimed to compare screening strategies including VFA and spine radiography (X-ray) for detecting VF in terms of clinical effectiveness, cost and radiation exposure. Methods: Three screening strategies: 1) X-ray following VFA, 2) VFA only, and 3) X-ray only were compared using a Markov model based on administrative data from South Korea in a population aged >= 50 years. We compared the incidence of new VFs, cost-effectiveness of reducing new VFs and radiation exposure in each strategy. Results: The incidence of new VFs was reduced in all screening strategies compared to no screening: 29.4% for women and 12.5% for men in both X-ray following the VFA and VFA only strategies and 35% for women and 17. 5% for men in the X-ray only strategy. The X-ray following VFA strategy had the lowest cost, followed by the X-ray only, and VFA only strategies. The radiation doses for X-ray only were 2,647-2,989 mu Sv and 3,253-3,398 mu Sv higher than in the X-ray following VFA and VFA only strategies. The new VF prevention effect was greater in women, and more prominent in older people (women >= 70, men >= 80) than people >= 50 years. Conclusions: The X-ray following VFA strategy is a cost-effective option for screening prevalent VF to prevent new VF in people aged >= 50 years due to its high effectiveness, lowest cost, and least radiation exposure.
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