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Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance
- Authors
- Yu, Hojeong; Kim, Kyujung; Ma, Kyungjae; Lee, Wonju; Choi, Joung-Woo; Yun, Chae-Ok; Kim, Donghyun
- Issue Date
- Mar-2013
- Publisher
- Pergamon Press Ltd.
- Keywords
- Localized surface plasmon resonance; Nanoislands; Adenovirus; Rigorous coupled-wave analysis; Transfer matrix method; Target-field overlap
- Citation
- Biosensors and Bioelectronics, v.41, pp 249 - 255
- Pages
- 7
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- Biosensors and Bioelectronics
- Volume
- 41
- Start Page
- 249
- End Page
- 255
- ISSN
- 0956-5663
1873-4235
- Abstract
- In this paper, we investigate localized surface plasmon resonance (SPR) detection based on nanoislands. Theoretical calculation performed with rigorous coupled-wave analysis and analytical transfer matrix method using effective medium theory suggests improvement on nanoislands in the limit of detection and sensitivity over conventional thin film-based SPR detection. Experimental results obtained with non-specific detection of ambient adenovirus confirm the improvement by more than one order of magnitude increase in the limit of detection. The enhancement achieved with nanoislands was explored in connection with efficient overlap between target and near-field distribution produced by nanoislands. (C) 2012 Elsevier B.V. All rights reserved.
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Related Researcher
- Yun, Chae Ok
- COLLEGE OF ENGINEERING (DEPARTMENT OF BIOENGINEERING)