위암의 화학 예방 요법: Helicobacter 제균 치료open accessChemoprevention of Gastric Cancer: Helicobacter pylori Eradication
- Other Titles
- Chemoprevention of Gastric Cancer: Helicobacter pylori Eradication
- Authors
- 김은진; 이항락
- Issue Date
- Dec-2017
- Publisher
- 대한상부위장관ㆍ헬리코박터학회
- Keywords
- Chemoprevention; Helicobacter pylori; Stomach neopla는
- Citation
- Korean Journal of Helicobacter Upper Gastrointestinal Research, v.17, no.4, pp.166 - 168
- Indexed
- KCI
OTHER
- Journal Title
- Korean Journal of Helicobacter Upper Gastrointestinal Research
- Volume
- 17
- Number
- 4
- Start Page
- 166
- End Page
- 168
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3423
- DOI
- 10.7704/kjhugr.2017.17.4.166
- ISSN
- 1738-3331
- Abstract
- Gastric cancer is one of the most common fatal malignancies in the world, with a high incidence in Korea and Japan. Helicobacter pylori infection is an important factor in the pathogenesis of gastric cancer. Epidemiological studies have shown a strong causal relationship between H. pylori infection and gastric cancer. Animal studies have also shown that eradication of H. pylori infection, especially at the early stage, is effective in preventing H. pylori-related gastric carcinogenesis. H. pylori eradication leads to regression and prevents the progression of gastric precancerous lesions but only in a minority of cases. H. pylori eradication appears to be the most promising approach for gastric cancer prevention. The current available data from human studies show that H. pylori eradication can reduce the risk of developing gastric cancer, and this strategy is more useful in patients without atrophic gastritis or intestinal metaplasia. A longer follow-up and additional studies are needed for a better understanding of this issue. (Korean J Helicobacter Up Gastrointest Res 2017;17:-168)
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