A Case of Refractory Oral Aphthous Ulcer Successfully Treated with Adalimumabopen accessA Case of Refractory Oral Aphthous Ulcer Successfully Treated with Adalimumab
- Other Titles
- A Case of Refractory Oral Aphthous Ulcer Successfully Treated with Adalimumab
- Authors
- 김진영; 송명진; 정혜진; 조수경; 성윤경
- Issue Date
- Jun-2017
- Publisher
- 대한류마티스학회
- Keywords
- Oral ulcer; Aphthous stomatitis; Tumor necrosis factor-alpha inhibitor; Adalimumab
- Citation
- 대한류마티스학회지, v.24, no.3, pp.157 - 160
- Indexed
- KCI
- Journal Title
- 대한류마티스학회지
- Volume
- 24
- Number
- 3
- Start Page
- 157
- End Page
- 160
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3530
- DOI
- 10.4078/JRD.2017.24.3.157
- ISSN
- 2093-940X
- Abstract
- Oral aphthous ulcer is a common lesion characterized by loss of dermal tissue of various shapes in many diseases. It is not serious, but may affect quality of life through pain and discomfort. In many cases, it heals spontaneously without treatment or with topical agents such as antiseptics, analgesics and corticosteroid in a few days. However, rarely, there are a few cases of aphthous ulcer that remain refractory despite appropriate treatment. Tumor necrosis factor-α inhibitors have recently been used in treatment of severe mucosal ulcer in Behçet’s disease. Herein, we report a patient suffering from refractory oral aphthous ulcers that were resistant to topical and systemic agents, but were successfully treated with adalimumab.
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