Pulmonary actinomycosis mimicking lung cancer on positron emission tomographyopen access
- Authors
- Choi, Hayoung; Lee, Hyun; Jeong, Suk Hyeon; Um, Sang-Won; Jung, Kown O.; Kim, Hojoong
- Issue Date
- Apr-2017
- Publisher
- MEDKNOW PUBLICATIONS & MEDIA PVT LTD
- Keywords
- Actinomycosis; diagnosis; lung neoplasms; positron emission tomography
- Citation
- ANNALS OF THORACIC MEDICINE, v.12, no.2, pp.121 - 124
- Indexed
- SCIE
SCOPUS
- Journal Title
- ANNALS OF THORACIC MEDICINE
- Volume
- 12
- Number
- 2
- Start Page
- 121
- End Page
- 124
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3545
- DOI
- 10.4103/1817-1737.203752
- ISSN
- 1817-1737
- Abstract
- Pulmonary actinomycosis frequently mimics lung malignancy on radiologic imaging studies. Positron emission tomography-computed tomography (PET-CT) is a useful diagnostic modality for differentiating lung malignancy from benign diseases. However, few studies evaluated PET-CT findings of pulmonary actinomycosis. Therefore, it is unclear whether PET-CT is helpful to distinguish lung malignancy from benign lung disease when pulmonary actinomycosis is clinically suspected. We investigated PET-CT findings in 11 patients with pathologically confirmed pulmonary actinomycosis. The median maximal standardized uptake value (SUV) on PET-CT of pulmonary actinomycosis was increased to 5.5 (interquartile range, 4.2-8.8), which was higher than the threshold value of 2.5 indicating malignancy. Pulmonary actinomycosis without central necrosis demonstrated higher maximal SUV of 7.5 (4.9-12.2) compared to 4.8 (3.2-5.6) of ones with central necrosis. PET-CT might be not helpful in differentiating lung malignancy from benign lesions when pulmonary actinomycosis is clinically suspected.
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