Liquid culture enhances diagnosis of patients with milder forms of non-tuberculous mycobacterial lung disease
- Authors
- Lee, Hyun; Han, Jinhyung; Park, Hye-yun; Jeon, Kyeongman; Huh, Hee-jae; Ki, Chang Seok; Lee, Nam-young; Koh, Wonjung
- Issue Date
- Mar-2017
- Publisher
- INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
- Keywords
- NTM; diagnosis; sputum microbiology; culture media
- Citation
- INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, v.21, no.3, pp.345 - 350
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Volume
- 21
- Number
- 3
- Start Page
- 345
- End Page
- 350
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3563
- DOI
- 10.5588/ijtld.16.0606
- ISSN
- 1027-3719
- Abstract
- OBJECTIVE: To evaluate the proportion and clinical characteristics of patients with non-tuberculous mycobacteria (NTM) lung disease diagnosed based on positive culture results in liquid medium only.
METHODS: We reviewed the medical records of 978 patients diagnosed with NTM lung disease. All clinical samples were cultured in both solid and liquid media.
RESULTS: Of the 978 patients, 111 (11.3%) were culture-positive in liquid medium only (liquid culture group), and 867 (88.7%) (solid culture group) on solid medium, regardless of the culture results in liquid medium. At the time of diagnosis, the liquid culture group was less likely than the solid culture group to have haemoptysis (11.7% vs. 20.0%, P = 0.04), positive sputum smear for acid-fast bacilli (14.4% vs. 50.2%, P ˂ 0.001) or the fibrocavitary form of NTM lung disease (3.6% vs. 14.6%, P=0.001). During the median follow-up period of 28.9 months (interquartile range 19.141.6), the proportion of patients requiring antibiotic treatment was lower in the liquid culture group than in the solid culture group (44.1% vs. 61.6%, P ˂ 0.001).
CONCLUSIONS: Liquid media culture is helpful in the diagnosis of patients with less severe forms of NTM lung disease.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/3563)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.