Highly sensitive detection of dipicolinic acid with a water-dispersible terbium-metal organic framework
- Authors
- Bhardwaj, Neha; Bhardwaj, Sanjeev; Mehta, Jyotsana; Kim, Ki-Hyun; Deep, Akash
- Issue Date
- Dec-2016
- Publisher
- ELSEVIER ADVANCED TECHNOLOGY
- Keywords
- Metal organic framework; Sensor; Fluorescence; Terbium; Dipicolinic acid
- Citation
- BIOSENSORS & BIOELECTRONICS, v.86, pp.799 - 804
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOSENSORS & BIOELECTRONICS
- Volume
- 86
- Start Page
- 799
- End Page
- 804
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4878
- DOI
- 10.1016/j.bios.2016.07.063
- ISSN
- 0956-5663
- Abstract
- The sensitive detection of dipicolinic acid (DPA) is strongly associated with the sensing of bacterial organisms in food and many types of environmental samples. To date, the demand for a sensitive detection method for bacterial toxicity has increased remarkably. Herein, we investigated the DPA detection potential of a water-dispersible terbium-metal organic framework (Tb-MOF) based on the fluorescence quenching mechanism. The Tb-MOF showed a highly sensitive ability to detect DPA at a limit of detection of 0.04 nM (linear range of detection: 1 nM to 5 mu tM) and also offered enhanced selectivity from other commonly associated organic molecules. The present study provides a basis for the application of Tb-MOF for direct, convenient, highly sensitive, and specific detection of DPA in the actual samples.
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