Application of MoS2 modified screen-printed electrodes for highly sensitive detection of bovine serum albumin
- Authors
- Kukkar, Manil; Sharma, Ashish; Kumar, Parveen; Kim, Ki-Hyun; Deep, Akash
- Issue Date
- Oct-2016
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- MoS2; Immunosensing; Bovine serum albumin; Cyclic voltammetry
- Citation
- ANALYTICA CHIMICA ACTA, v.939, pp.101 - 107
- Indexed
- SCIE
SCOPUS
- Journal Title
- ANALYTICA CHIMICA ACTA
- Volume
- 939
- Start Page
- 101
- End Page
- 107
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4945
- DOI
- 10.1016/j.aca.2016.08.010
- ISSN
- 0003-2670
- Abstract
- The present work reports the application of a new molybdenum disulphide (MoS2)-based electrochemical platform for highly sensitive quantitation of an iron-binding protein, bovine serum albumin (BSA). The gold screen-printed electrodes were modified with MoS2 nanoflakes, followed by bio-conjugation with anti-BSA antibodies. Using the above bioelectrode, cyclic voltammetric analysis was carried out in the presence of a Fe3+/Fe2+ redox probe which exhibited a linear response of peak current with varying concentrations of BSA up to 10 ng/mL (with a detection limit of 0.006 ng/mL). This study is novel in that it shows a considerable enhancement of signal during electrochemical sensing of a protein.
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