Optimal boundary detection method and window settings for coronary atherosclerotic plaque volume analysis in coronary computed tomography angiography: comparison with intravascular ultrasound
- Authors
- Heo, Ran; Park, Hyung-Bok; Lee, Byoung Kwon; Shin, Sanghoon; Arsanjani, Reza; Min, James K.; Chang, Hyuk-Jae
- Issue Date
- Sep-2016
- Publisher
- SPRINGER
- Keywords
- Coronary CT angiography; Quantitative plaque volume analysis; Boundary detection; Window settings; Intravascular ultrasound
- Citation
- EUROPEAN RADIOLOGY, v.26, no.9, pp.3190 - 3198
- Indexed
- SCIE
SCOPUS
- Journal Title
- EUROPEAN RADIOLOGY
- Volume
- 26
- Number
- 9
- Start Page
- 3190
- End Page
- 3198
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4954
- DOI
- 10.1007/s00330-015-4121-5
- ISSN
- 0938-7994
- Abstract
- Objective: To evaluate optimal methodology for quantitative plaque volume analysis by coronary CT angiography (QCT).
Methods: Fifty-one coronary artery segments were evaluated and contour measurements based on two different methods [(1) no gap, or (2) fixed 0.3-mm gap between inner and outer boundary] were compared with intravascular ultrasound (IVUS). In addition, three different window width (WW) and level (WL) settings [fixed (740/220) Hounsfield unit (HU), adjusted (155 % and 65 % of mean luminal intensity of the segment, and aorta adjusted (155 % and 65 % of mean luminal intensity of central aorta)] were used for semiautomated plaque volume analysis.
Results: For boundary detection, the no gap method led to underestimation compared with IVUS (105.4 ± 82.3 vs. 136.1 ± 72.8 mm³, p < 0.001), while fixed 0.3-mm gap showed no difference between IVUS and QCT (136.1 ± 72.8 vs. 139.8 ± 93.9 mm³, p = 0.50). Comparison of the three different window settings demonstrated that the aorta adjusted setting underestimated (120.5 ± 74.3 vs. 136.1 ± 72.8 mm³, p = 0.003), while fixed setting showed the least mean difference compared with IVUS (3.8 ± 39.8 mm³, p = 0.50).
Conclusion: For plaque volumetric assessment, optimal results were obtained with fixed 0.3-mm gap with fixed HU setting (740/220).
Key points: • Quantitative plaque volume analysis by coronary CT angiography has recently emerged. • Different boundary detection methods and window width and level settings were evaluated. • Fixed 0.3-mm gap with fixed HU setting (740/220) afforded optimal results.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.