Overhydration Negatively Affects Quality of Life in Peritoneal Dialysis Patients: Evidence from a Prospective Observational Studyopen access
- Authors
- Yoon, Hye Eun; Kwon, Young Joo; Song, Ho Cheol; Kim, Jin Kuk; Song, Young Rim; Shin, Seok Joon; Kim, Hyung Wook; Lee, Chang Hwa; Lee, Tae Won; Kim, Young Ok; Kim, Byung Soo; Moon, Kyoung Hyoub; Chang, Yoon Kyung; Kim, Seong Suk; Bang, Kitae; Cho, Jong Tae; Yun, Sung Ro; Na, Ki Ryang; Kim, Yang Wook; Han, Byoung Geun; Chung, Jong Hoon; Lee, Kwang Young; Jeong, Jong Hyeok; Hwang, Eun Ah; Kim, Yong-Soo
- Issue Date
- Aug-2016
- Publisher
- IVYSPRING INT PUBL
- Keywords
- bioimpedance; fluid overload; overhydration; peritoneal dialysis; quality of life
- Citation
- International Journal of Medical Sciences, v.13, no.9, pp.686 - 695
- Indexed
- SCIE
SCOPUS
- Journal Title
- International Journal of Medical Sciences
- Volume
- 13
- Number
- 9
- Start Page
- 686
- End Page
- 695
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4980
- DOI
- 10.7150/ijms.16372
- ISSN
- 1449-1907
- Abstract
- Backgound: This study evaluated whether the hydration status affected health-related quality of life (HRQOL) during 12 months in peritoneal dialysis (PD) patients.
Methods: The hydration status and the HRQOL were examined at baseline and after 12 months using a bioimpedance spectroscopy and Kidney Disease Quality of Life-Short Form, respectively in PD patients. Four hundred eighty-one patients were included and divided according to the baseline overhydration (OH) value; normohydration group (NH group, -2L≤ OH ≤+2L, n=266) and overhydration group (OH group, OH >+2L, n=215). Baseline HRQOL scores were compared between the two groups. The subjects were re-stratified into quartiles according to the OH difference (OH value at baseline - OH value at 12 months; <-1, -1 - -0.1, -0.1 - +1, and ≥+1L). The relations of OH difference with HRQOL scores at 12 months and the association of OH difference with the HRQOL score difference (HRQOL score at baseline - HRQOL score at 12 months) were assessed.
Results: The OH group showed significantly lower baseline physical and mental health scores (PCS and MCS), and kidney disease component scores (KDCS) compared with the NH group (all, P<0.01). At 12 months, the adjusted PCS, MCS, and KDCS significantly increased as the OH difference quartiles increased (P<0.001, P=0.002, P<0.001, respectively). In multivariate analysis, the OH difference was independently associated with higher PCS (β = 2.04, P< .001), MCS (β=1.02, P=0.002), and KDCS (β=1.06, P<0.001) at 12 months. The OH difference was independently associated with the PCS difference (β = -1.81, P<0.001), MCS difference (β=-0.92, P=0.01), and KDCS difference (β=-0.90, P=0.001).
Conclusion: The hydration status was associated with HRQOL and increased hydration status negatively affected HRQOL after 12 months in PD patients.
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